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The Dangers of Combining Cymbalta Duloxetine and Alcohol

We provide ongoing support through aftercare programs designed to help you maintain sobriety and continue thriving. This evaluation allows us to create a tailored treatment plan that addresses your specific needs. At Long Island Interventions, we understand that overcoming alcohol use can feel overwhelming, especially when combined with medications like Cymbalta. This competition can lead to higher blood concentrations of both substances remaining in the system for longer periods. The medication is highly protein-bound in the bloodstream and is metabolized primarily in the liver before being eliminated through urine. This class of medications works by affecting the balance of certain neurotransmitters in the brain.

Amplification of Side Effects

  • In this article, we will understand what duloxetine is used for and how duloxetine interacts with alcohol and other drugs.
  • If you are withdrawing from alcohol, however, you should never take Cymbalta or other medications containing duloxetine without first consulting your doctor.
  • The medication is highly protein-bound in the bloodstream and is metabolized primarily in the liver before being eliminated through urine.
  • Common side effects include dry mouth, blurred vision, abdominal pain, nausea, and irregular heart rates.
  • This competition can lead to higher blood concentrations of both substances remaining in the system for longer periods.

Duloxetine is a serotonin and noradrenaline reuptake inhibitor, commonly marketed as Cymbalta, prescribed for depression, anxiety and pain conditions. In this article, we will understand what duloxetine is used for and how duloxetine interacts with alcohol and other drugs. Chronic alcohol abuse damages liver tissue, causes alcoholic liver disease, and disrupts mental health stability. It contributes to alcohol withdrawal symptoms like anxiety-related alcohol use, tremors, irritability, and insomnia. Yes, alcohol can worsen depression or anxiety symptoms while taking Cymbalta. Alcohol is a central nervous system depressant, and excessive consumption can exacerbate depressive symptoms and increase feelings of anxiety.

What You Should Know About Cymbalta and Alcohol

Honest discussions about alcohol use disorders, alcohol intake, and alcohol metabolism allow healthcare professionals to recommend safer treatment options. This medication can have various effects on your body and may create unwanted side effects if you mix it with alcohol or other substances. If you are taking Cymbalta, it is crucial to know the potential side effects, interactions, and risks of mixing this medication with alcohol. Cymbalta is a brand name for duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI)prescribed to treat various conditions including anxiety and depression. It is not fully clear how duloxetine achieves antidepressant properties, but it is hypothesized it is through increasing the availability of serotonin in the brain. Increased noradrenaline can supplement increases in cognitive function 6.

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The Dangers of Combining Cymbalta (Duloxetine) and Alcohol

If your doctor allows it, you should discuss how much is a safe amount of alcohol while you take this drug. It can have serious effects on your body, especially when mixed with other substances such as alcohol. If you are thinking about trying Cymbalta for depression, anxiety, or other illness, discuss your options with your doctor.

What will happen if I drink alcohol while taking duloxetine?

The FDA reports that when Cymbalta and alcohol are taken so that their peak effects coincide, the use of Cymbalta did not worsen the motor or mental impairment caused by alcohol. However, combining the two substances may contribute to a worsening of other side effects. If you or a loved one is struggling with an alcohol use disorder, or if abstaining from alcohol proves to be a challenge while on medications like Cymbalta, know that help is available.

If you are trying to stop drinking or if you have recently quit, talk to your doctor about whether Cymbalta might be an option. Some research suggests that duloxetine may be useful in lessening anxiety-like behaviors and alcohol intake, which may make it useful as a treatment during alcohol withdrawal. You should never stop taking Cymbalta or any other medication abruptly without consulting with your doctor. If you experience side effects or have concerns, it’s essential to seek medical advice.

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However, if you or a loved one is unable to stop alcohol abuse because of the withdrawal symptoms, you may ask your healthcare provider to change your medication. Additionally, alcohol can worsen certain conditions that Cymbalta is prescribed to treat, such as depression and anxiety. Mixing Cymbalta and alcohol can also increase the risk of overdose or other serious health complications. Experts like Christina Aungst, Austin Ulrich, and Stacia Woodcock highlight these dangers. Leading pharmacy editors and researchers like Weiner JL, Skelly MJ, and governmental agencies stress the need for a decrease in drinking during any antidepressant use.

  • Other substances that can interact with Cymbalta include other antidepressants, blood thinners, and St. John’s wort.
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  • Cymbalta and alcohol affect the central nervous system through different mechanisms.
  • Each medication is different, so don’t assume that because it was okay to drink when taking another antidepressant, it will also be alright to consume alcohol when taking something else.
  • Alcohol is a sedative that increases the release of GABA, an inhibitory neurotransmitter, in the brain.

How Does Drinking on Cymbalta Affect the Body?

Following the guidance of healthcare providers prevents adverse effects and harmful interactions. Mixing the two substances raises the likelihood of blackouts, memory loss, and binge-like ethanol behaviors. Acute ethanol self-administration can trigger excitatory effects on the brain, reducing judgment and impairing emotional regulation. This risk is especially dangerous for people already facing mental health conditions.

Other substances that can interact with Cymbalta include other antidepressants, blood thinners, and St. John’s wort. If you are withdrawing from alcohol, however, you should never take Cymbalta or other medications containing duloxetine without first consulting your doctor. Your doctor can evaluate your health and guide you through the withdrawal process based on your unique needs and situation. One study found that treatment with a low dose of duloxetine significantly decreased alcohol use. The study also found that this decrease in drinking was also accompanied by a drop in anxiety-related behaviors.

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Continue for 0.2 miles.Use the 2nd from the right lane to turn slightly right onto S Sepulveda Blvd (signs for I-105). Merge onto I-105 E. Continue for approximately 17 miles.Use the right 2 lanes to merge onto I-605 S towards Long Beach. Continue on I-405 S for approximately 38 miles.Take exit 92 for Bake Pkwy. Drive for about 0.3 miles.Turn right onto Bake Pkwy (signs for Bake Parkway/Irvine Spectrum Center). Continue on Bake Pkwy for about 2.6 miles.Turn right onto Birtcher Dr.Your destination, Birtcher Dr, Lake Forest, CA 92630, will be on your right. Be sure that you do not stop taking your antidepressant or change your dosage without first talking to your doctor.

IOP For Anxiety: Stop Panic With A Strong Plan

If you are taking Cymbalta and want to know if having a drink or two is safe, talk to your doctor. Because they understand your situation and history, they can make recommendations based on your needs and health. Shannon Weir, RN is the Chief Nursing Officer at Gallus Medical Detox Centers. She has been a Registered Nurse for 30 years, Shannon’s experience ranges from critical care to flight nursing, medical detox, sexual assault exams, and SWAT nursing. Shannon has been with Gallus Medical Detox Centers since 2010 and is a vital part of our organization. Abrupt discontinuation of Duloxetine may result in discontinuation-emergent adverse events, of which dizziness was reported in 12% of patients.

Alcohol’s disruption of central noradrenergic signaling and serotonin levels leads can you drink alcohol with cymbalta to unpredictable emotional swings. Both alcohol and duloxetine stress the liver, increasing the risk of liver damage and alcoholic liver disease. Heavy drinkers may develop liver disease faster when taking Cymbalta, as the body struggles to filter toxins. Warning signs like dark-colored urine, abdominal pain, and increased liver enzyme levels often indicate symptoms of liver damage requiring urgent medical attention.